General Information of Drug Metabolite (DM) (ID: DM001419)
DM Name
R-bicalutamide-glucuronide
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A8 (UGT1A8) DME0064 Unclear - Unclear Bicalutamide [1] , [2]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME0042 Unclear - Unclear Bicalutamide [1] , [2]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Unclear - Unclear Bicalutamide [1] , [2]
Full List of Drug(s) That Produce This DM By Metabolism
Bicalutamide DR0210 Approved Prostate cancer
References
1 Enantiomer selective glucuronidation of the non-steroidal pure anti-androgen bicalutamide by human liver and kidney: role of the human UDP-glucuronosyltransferase (UGT)1A9 enzyme Basic Clin Pharmacol Toxicol. 2013 Aug;113(2):92-102. doi: 10.1111/bcpt.12071.
2 Dailymed:Bicalutamide

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