| General Information of Drug Metabolite (DM) (ID: DM001419) |
| DM Name |
R-bicalutamide-glucuronide
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 1A8 (UGT1A8)
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DME0064
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| Unclear - Unclear |
Bicalutamide
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[1] , [2] |
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UDP-glucuronosyltransferase 1A9 (UGT1A9)
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DME0042
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| Unclear - Unclear |
Bicalutamide
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[1] , [2] |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Unclear - Unclear |
Bicalutamide
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[1] , [2] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Bicalutamide |
DR0210
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Approved |
Prostate cancer |
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| References |
| 1 |
Enantiomer selective glucuronidation of the non-steroidal pure anti-androgen bicalutamide by human liver and kidney: role of the human UDP-glucuronosyltransferase (UGT)1A9 enzyme Basic Clin Pharmacol Toxicol. 2013 Aug;113(2):92-102. doi: 10.1111/bcpt.12071.
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| 2 |
Dailymed:Bicalutamide
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