Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000437)
Formula Reactant Brexpiprazole Product Brexpiprazole metabolite M7
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000438 Brexpiprazole Brexpiprazole metabolite M3 Unclear Brexpiprazole [1], [2]
MR000439 Brexpiprazole Brexpiprazole metabolite M5 Unclear Brexpiprazole [1], [2]
MR000441 Brexpiprazole Brexpiprazole metabolite M6 Unclear Brexpiprazole [1], [2]
MR000440 Brexpiprazole Brexpiprazole metabolite M8 Unclear Brexpiprazole [1], [2]
MR000436 Brexpiprazole Brexpiprazole S-oxide Unclear Brexpiprazole [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000435 Brexpiprazole metabolite M7 Brexpiprazole metabolite M7-glucuronide Unclear Brexpiprazole [1], [2]
References
1 Brexpiprazole: first global approval. Drugs. 2015 Sep;75(14):1687-97.
2 Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human. Xenobiotica. 2021 May;51(5):590-604. doi: 10.1080/00498254.2021.1890275.

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