Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000440)
Formula Reactant Brexpiprazole Product Brexpiprazole metabolite M8
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000438 Brexpiprazole Brexpiprazole metabolite M3 Unclear Brexpiprazole [1], [2]
MR000439 Brexpiprazole Brexpiprazole metabolite M5 Unclear Brexpiprazole [1], [2]
MR000441 Brexpiprazole Brexpiprazole metabolite M6 Unclear Brexpiprazole [1], [2]
MR000437 Brexpiprazole Brexpiprazole metabolite M7 Unclear Brexpiprazole [1], [2]
MR000436 Brexpiprazole Brexpiprazole S-oxide Unclear Brexpiprazole [1], [2]
References
1 Brexpiprazole: first global approval. Drugs. 2015 Sep;75(14):1687-97.
2 Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human. Xenobiotica. 2021 May;51(5):590-604. doi: 10.1080/00498254.2021.1890275.

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