Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000471)
Formula
SVG example
Hydroxylation
Reactant Budesonide Product 22-hydroxy Intermediate metabolite of Budesonide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000474 Budesonide 23-hydroxybudesonide Oxidation - Hydroxylation Budesonide [1]
MR000472 Budesonide 6-beta-hydroxybudesonide Oxidation - Hydroxylation Budesonide [1]
MR000473 Budesonide Delta-6-budesonide Unclear Budesonide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000469 22-hydroxy Intermediate metabolite of Budesonide 16alpha-butyrloxyprednisolone Unclear Budesonide [1]
References
1 Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes. Drug Metab Dispos. 2013 Feb;41(2):379-89.

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