Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000537)
Formula	Monohydroxy Sulphation
	Reactant	Cabozantinib	Product	EXEL-1646
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Conjugation - Monohydroxy Sulphation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR000536	Cabozantinib	4-Fluoroaniline	Unclear	Cabozantinib	[1]
MR000538	Cabozantinib	EXEL-5162	Oxidation - N-Oxidation	Cabozantinib	[1]
MR000535	Cabozantinib	EXEL-5366	Unclear	Cabozantinib	[1]

References
1	Clinical Pharmacokinetics and Pharmacodynamics of Cabozantinib Clin Pharmacokinet. 2017 May;56(5):477-491. doi: 10.1007/s40262-016-0461-9.

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