General Information of This Metabolic Reaction (MR) (ID: MR000578)
Formula
SST
SVG example
Reactant CCG-205124 Product Spermine
Reactant Info Product Info
Metabolic Enzyme Somatostatin (SST) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000579 CCG-205124 N-Acetylspermidine Unclear CCG-205124 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007653 Putrescine Spermine Other reaction - Decarboxylation Putrescine [2]
MR003068 Spermidine Spermine Unclear Agmatine [3], [4], [5]
MR012736 Spermidine Spermine Unclear - Unclear Arginine [6]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000575 Spermine N--Acetylspermine Unclear CCG-205124 [1]
MR003069 Spermine N-AcSpm Unclear Agmatine [3]
References
1 The Association between Spermidine/Spermine N(1)-Acetyltransferase (SSAT) and Human Malignancies Int J Mol Sci. 2022 May 25;23(11):5926. doi: 10.3390/ijms23115926.
2 Human aldehyde dehydrogenase: metabolism of putrescine and histamine
3 Metabolism and function in animal tissues of agmatine, a biogenic amine formed from arginine Amino Acids. 2004 Feb;26(1):3-8. doi: 10.1007/s00726-003-0030-z.
4 Genome-wide analysis of polyamine biosynthesis genes in wheat reveals gene expression specificity and involvement of STRE and MYB-elements in regulating polyamines under drought. BMC Genomics. 2022 Oct 30;23(1):734. doi: 10.1186/s12864-022-08946-2.
5 Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 Mar 25;12(4):501. doi: 10.3390/biom12040501.
6 Arginine Metabolism Revisited

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