Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000611)
Formula Reactant Cevimeline hydrochloride Product Cevimeline cis-sulfoxidation
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Sulfoxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000610 Cevimeline hydrochloride Cevimeline cis-sulfoxide Unclear Cevimeline hydrochloride [1]
MR000613 Cevimeline hydrochloride Cevimeline glucuronic acid Unclear Cevimeline hydrochloride [1]
MR000612 Cevimeline hydrochloride Cevimeline N-oxide Unclear Cevimeline hydrochloride [1]
MR000609 Cevimeline hydrochloride Cevimeline trans-sulfoxide Oxidation - Sulfoxidation Cevimeline hydrochloride [1]
References
1 Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011. Biol Pharm Bull. 2001 Nov;24(11):1263-6.

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