Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000609)
Formula
CYP3A4 ...
SVG example
Sulfoxidation
Reactant Cevimeline hydrochloride Product Cevimeline trans-sulfoxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Sulfoxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000611 Cevimeline hydrochloride Cevimeline cis-sulfoxidation Oxidation - Sulfoxidation Cevimeline hydrochloride [1]
MR000610 Cevimeline hydrochloride Cevimeline cis-sulfoxide Unclear Cevimeline hydrochloride [1]
MR000613 Cevimeline hydrochloride Cevimeline glucuronic acid Unclear Cevimeline hydrochloride [1]
MR000612 Cevimeline hydrochloride Cevimeline N-oxide Unclear Cevimeline hydrochloride [1]
References
1 Identification of human drug-metabolizing enzymes involved in the metabolism of SNI-2011. Biol Pharm Bull. 2001 Nov;24(11):1263-6.

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