Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000795)
Formula
SVG example
5-Hydroxylation
Reactant Dexlansoprazole Product 5-hydroxy dexlansoprazole
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - 5-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000796 Dexlansoprazole 4-sulfonyloxy dexlansoprazole Conjugation - Sulfation Dexlansoprazole [1]
MR000794 Dexlansoprazole Lansoprazole Sulfone Oxidation - Oxidation Dexlansoprazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000793 5-hydroxy dexlansoprazole 5-glucuronyloxy dexlansoprazol Conjugation - Glucuronidation Dexlansoprazole [1]
References
1 Absorption, distribution, metabolism and excretion of [14C]dexlansoprazole in healthy male subjects. Clin Drug Investig. 2012 May 1;32(5):319-32.

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