Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000909)
Formula
SVG example
Reactant Eplerenone Product 6beta-hydroxyeplerenone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000910 Eplerenone 21-hydroxyeplerenone Oxidation - Hydroxylation Eplerenone [1]
References
1 The relative role of CYP3A4 and CYP3A5 in eplerenone metabolism. Toxicol Lett. 2019 Oct 15;315:9-13.

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