Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000910)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant Eplerenone Product 21-hydroxyeplerenone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000909 Eplerenone 6beta-hydroxyeplerenone Unclear Eplerenone [1]
References
1 The relative role of CYP3A4 and CYP3A5 in eplerenone metabolism. Toxicol Lett. 2019 Oct 15;315:9-13.

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