Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001003)
Formula Reactant Exenatide Product Small peptides
Reactant Info Product Info
Metabolic Enzyme Metalloprotease (MMP) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001004 Exenatide Exendin-4(15C39) Unclear Exenatide [1]
MR001005 Exenatide Exendin-4(16C39) Unclear Exenatide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005594 Setmelanotide Small peptides Unclear Setmelanotide [2]
MR010739 Unclear Small peptides Unclear - Unclear Plecanatide [3]
References
1 In vitro metabolic stability of exendin-4: pharmacokinetics and identification of cleavage products. PLoS One. 2015 Feb 27;10(2):e0116805.
2 DrugBank(Pharmacology-Metabolism):Spironolactone
3 Plecanatide for the treatment of chronic idiopathic constipation in adult patients

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