General Information of This Metabolic Reaction (MR) (ID:
MR001079) |
Formula |
|
Reactant |
Fluvoxamine maleate |
Product |
Fluvoxamine alcohol |
Reactant Info
|
Product Info
|
Metabolic Enzyme
|
Cytochrome P450 1A2 (CYP1A2)
|
DME Info
|
Cytochrome P450 2D6 (CYP2D6)
|
DME Info
|
Metabolic Type
|
Oxidation
-
O-Dealkylation
|
|
|
|
|
|
|
|
Other MR(s) Related to The Reactant of This MR |
Other MR(s) That Metabolize The Reactant of This MR
|
|
Other MR(s) Related to The Product of This MR |
Other MR(s) That Produce The Product of This MR
|
|
References |
1 |
U. S. FDA Label -Fluvoxamine maleate
|
2 |
DrugBank(Pharmacology-Metabolism)Fluvoxamine maleate
|
3 |
Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.