Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001153)
Formula	CYP1A1 Hydoxylation
	Reactant	Granisetron hydrochloride	Product	7-hydroxygranisetron
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 1A1 (CYP1A1)				DME Info
Metabolic Type	Oxidation - Hydoxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001152	Granisetron hydrochloride	9'-desmethylgranisetron	Oxidation - Demethylation	Granisetron hydrochloride	[1]

References
1	Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron. Br J Clin Pharmacol. 1994 Dec;38(6):557-66.

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