Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001330)
Formula
SVG example
Reactant Dihydroxy ketobemidone Product p-hydroxymethoxy ketobemidone
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001335 Ketobemidone Dihydroxy ketobemidone Unclear Ketobemidone [1]
MR003315 Melatonin Dihydroxy ketobemidone Oxidation - O-Demethylation Melatonin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001331 Dihydroxy ketobemidone M-hydroxymethoxy ketobemidone Unclear Ketobemidone [1]
MR003309 Dihydroxy ketobemidone N-Acetyl-5-hydroxytryptamine glucuronide metabolite Conjugation - Glucuronidation Melatonin [1]
MR003310 Dihydroxy ketobemidone N-Acetyl-5-hydroxytryptamine sulfate metabolite Other reaction - Sulfonation Melatonin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001332 p-hydroxymethoxy ketobemidone p-hydroxymethoxy ketobemidone glucuronide metabolite Unclear Ketobemidone [2]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2 In vivo investigation of brain and systemic ketobemidone metabolism Analyst. 2010 Feb;135(2):405-13. doi: 10.1039/b917940b.

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