Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001334)
Formula
	Reactant	Norketobemidone	Product	Norketobemidone glucuronide metabolite
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001336	Ketobemidone	Norketobemidone	Oxidation - N-Demethylation	Ketobemidone	[1], [2]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001333	Norketobemidone	Dihydroxy norketobemidone	Oxidation - 4'-Hydroxylation	Ketobemidone	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
2	Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein. Xenobiotica. 2005 Aug;35(8):785-96.

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