Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001339)
Formula Reactant M8 (Ketoconazole) Product M6 (Ketoconazole)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001355 Ketoconazole M8 (Ketoconazole) Oxidation - Hydroxylation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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