Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001342)
Formula Reactant M9 (Ketoconazole) Product M12 (Ketoconazole)
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001356 Ketoconazole M9 (Ketoconazole) Oxidation - Hydoxylation Ketoconazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001341 M9 (Ketoconazole) Ketoconazole iminium ion Other reaction - Dehydration Ketoconazole [1]
MR001340 M9 (Ketoconazole) M10 (Ketoconazole) Oxidation - N-Dealkylation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

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