Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001369)
Formula
SVG example
Glucuronidation
Reactant Ketorolac Product Rac Ketorolac glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001368 Ketorolac 4-hydroxy ketorolac Oxidation - Hydroxylation Ketorolac [1]
MR001370 Ketorolac K1 Unclear Ketorolac [1]
MR001374 Ketorolac K2 Unclear Ketorolac [1]
MR001373 Ketorolac K6 Conjugation - Methylation Ketorolac [1]
MR001372 Ketorolac K7 Conjugation - Acetylation Ketorolac [1]
MR001371 Ketorolac K8 Conjugation - Sulfation Ketorolac [1]
References
1 Identification and structural characterization of in vivo metabolites of ketorolac using liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) J Mass Spectrom. 2012 Jul;47(7):919-31. doi: 10.1002/jms.3043.

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