Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR001615)
Formula	N-Oxidation
	Reactant	Medifoxamine		Product	N-oxide medifoxamine
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Oxidation - N-Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001616	Medifoxamine	Acidic medifoxamine	Unclear	Medifoxamine	[1]
MR001617	Medifoxamine	Hydroxymedifoxamine	Oxidation - Hydroxylation	Medifoxamine	[2]
MR001614	Medifoxamine	N-desmethylmedifoxamine	Oxidation - N-Demethylation	Medifoxamine	[3]

References
1	Solid-phase extraction of diltiazem and its metabolites from plasma prior to high-performance liquid chromatography J Chromatogr. 1990 Jun 29;528(2):542-6. doi: 10.1016/s0378-4347(00)82416-0.
2	Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors J Clin Invest. 1990 Aug;86(2):385-91. doi: 10.1172/JCI114723.
3	Measurement of medifoxamine metabolites in urine by high-performance liquid chromatography J Chromatogr. 1990 Jun 29;528(2):531-6. doi: 10.1016/s0378-4347(00)82414-7.

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