Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001616)
Formula Reactant Medifoxamine Product Acidic medifoxamine
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001617 Medifoxamine Hydroxymedifoxamine Oxidation - Hydroxylation Medifoxamine [1]
MR001614 Medifoxamine N-desmethylmedifoxamine Oxidation - N-Demethylation Medifoxamine [2]
MR001615 Medifoxamine N-oxide medifoxamine Oxidation - N-Oxidation Medifoxamine [3]
References
1 Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors J Clin Invest. 1990 Aug;86(2):385-91. doi: 10.1172/JCI114723.
2 Measurement of medifoxamine metabolites in urine by high-performance liquid chromatography J Chromatogr. 1990 Jun 29;528(2):531-6. doi: 10.1016/s0378-4347(00)82414-7.
3 Simple and practical high-performance liquid chromatographic assay of propofol in human blood by phenyl column chromatography with electrochemical detection J Chromatogr. 1990 Jun 29;528(2):537-41. doi: 10.1016/s0378-4347(00)82415-9.

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