Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001622)
Formula
SVG example
Hydroxylation
Reactant Medroxyprogesterone acetate Product 1beta-hydroxymedroxyprogesterone acetate
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001621 Medroxyprogesterone acetate 2beta-hydroxymedroxyprogesterone acetate Oxidation - Hydroxylation Medroxyprogesterone acetate [1]
MR001620 Medroxyprogesterone acetate 6beta-hydroxymedroxyprogesterone Acetate Oxidation - Hydroxylation Medroxyprogesterone acetate [1]
References
1 Metabolic profiling and cytochrome P450 reaction phenotyping of medroxyprogesterone acetate. Drug Metab Dispos. 2008 Nov;36(11):2292-8.

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