Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001621)
Formula
SVG example
Hydroxylation
Reactant Medroxyprogesterone acetate Product 2beta-hydroxymedroxyprogesterone acetate
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001622 Medroxyprogesterone acetate 1beta-hydroxymedroxyprogesterone acetate Oxidation - Hydroxylation Medroxyprogesterone acetate [1]
MR001620 Medroxyprogesterone acetate 6beta-hydroxymedroxyprogesterone Acetate Oxidation - Hydroxylation Medroxyprogesterone acetate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001619 2beta-hydroxymedroxyprogesterone acetate 2beta-,6beta-dihydroxymedroxyprogesterone acetate Oxidation - Hydroxylation Medroxyprogesterone acetate [1]
References
1 Metabolic profiling and cytochrome P450 reaction phenotyping of medroxyprogesterone acetate. Drug Metab Dispos. 2008 Nov;36(11):2292-8.

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