Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR001719)
Formula	CYP2C19 Hydroxylation
	Reactant	Nelfinavir mesylate		Product	Nelfinavir hydroxyl-t- butylamide
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Mephenytoin 4-hydroxylase (CYP2C19)					DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001721	Nelfinavir mesylate	2-methoxy-3-hydroxynelfinavir	Unclear	Nelfinavir mesylate	[1]
MR001720	Nelfinavir mesylate	3,4-Dihydroxynelfinavir	Oxidation - Hydroxylation	Nelfinavir mesylate	[1]

References
1	Conversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19 Drug Metab Dispos. 2004 Dec;32(12):1462-7. doi: 10.1124/dmd.104.001743.

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