Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001738)
Formula
SVG example
Dehydrogenation
Reactant Nifedipine Product Dehydronifedipine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001737 Nifedipine 2,6-dimethyl-4-(2-nitrophenyl)-5-methoxycarbonyl-pyridine-3-carboxylic acid Unclear Nifedipine [1]
References
1 Pharmacokinetics and metabolism of nifedipine Hypertension. 1983 Jul-Aug;5(4 Pt 2):II18-24. doi: 10.1161/01.hyp.5.4_pt_2.ii18.

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