Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001757)
Formula
SVG example
Reactant Nisoldipine metabolite M13 Product Nisoldipine metabolite M2
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001760 Nisoldipine Nisoldipine metabolite M13 Oxidation - Dehydrogenation Nisoldipine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001756 Nisoldipine metabolite M13 Nisoldipine metabolite M10 Unclear Nisoldipine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009739 Furnidipine Furnidipine M-2 Unclear - Unclear Furnidipine [2], [3]
MR001758 Nisoldipine metabolite M1 Nisoldipine metabolite M2 Oxidation - Dehydrogenation Nisoldipine [1]
References
1 Clinical pharmacokinetics of nisoldipine coat-core Clin Pharmacokinet. 1998 Sep;35(3):191-208. doi: 10.2165/00003088-199835030-00003.
2 Dihydropyridines' metabolites-induced early apoptosis after myocardial infarction in rats; new outlook on preclinical study with M-2 and M-3
3 Cardioprotective effects of an active metabolite of furnidipine in 2 models of isolated heart and on in vivo ischemiaCinduced and reperfusion-induced arrhythmias in rats

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