Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001760)
Formula
SVG example
Dehydrogenation
Reactant Nisoldipine Product Nisoldipine metabolite M13
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001761 Nisoldipine Nisoldipine metabolite M1 Unclear Nisoldipine [1]
MR001759 Nisoldipine Nisoldipine metabolite M9 Unclear Nisoldipine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001756 Nisoldipine metabolite M13 Nisoldipine metabolite M10 Unclear Nisoldipine [1]
MR001757 Nisoldipine metabolite M13 Nisoldipine metabolite M2 Unclear Nisoldipine [2]
References
1 Clinical pharmacokinetics of nisoldipine coat-core Clin Pharmacokinet. 1998 Sep;35(3):191-208. doi: 10.2165/00003088-199835030-00003.
2 Pharmacokinetics and metabolism of nilutamide Urology. 1991;37(2 Suppl):13-9. doi: 10.1016/0090-4295(91)80096-p.

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