Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001823)
Formula Reactant Olopatadine Product Olopatadine N-oxide metabolite
Reactant Info Product Info
Metabolic Enzyme Dimethylaniline oxidase 1 (FMO1) DME Info
Dimethylaniline oxidase 3 (FMO3) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001821 Olopatadine N-desmethyl olopatadine Oxidation - N-Demethylation Olopatadine [1]
MR001822 Olopatadine Olopatadine metabolite M5 Conjugation - Sulfation Olopatadine [1]
References
1 Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities. Drug Metab Dispos. 2002 Dec;30(12):1504-11.

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