Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001866)
Formula
SVG example
Oxidation
Reactant R-licarbazepine Product Cis-10,11-Dihydroxy-10,11-dihydrocarbamazepine
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001872 Oxcarbazepine R-licarbazepine Reduction - Reduction Oxcarbazepine [1]
MR000950 Oxcarbazepine R-licarbazepine Reduction - Reduction Eslicarbazepine acetate [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001865 R-licarbazepine R-Licarbazepine glucuronide Conjugation - O-Glucuronidation Oxcarbazepine [3]
MR001868 R-licarbazepine S-Licarbazepine glucuronide Conjugation - O-Glucuronidation Oxcarbazepine [3]
MR001867 R-licarbazepine Trans-10,11-dihydro-10,11-dihydroxycarbamazepine Oxidation - Oxidation Oxcarbazepine [3]
References
1 The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7.
2 U. S. FDA Label -Eslicarbazepine acetate
3 DrugBank(Pharmacology-Metabolism)Oxcarbazepine

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