Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001870)
Formula
SVG example
O-Glucuronidation
Reactant Oxcarbazepine Product Oxcarbazepine glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - O-Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001871 Oxcarbazepine Eslicarbazepine Reduction - Reduction Oxcarbazepine [1]
MR001869 Oxcarbazepine Oxcarbazepine alcohol sulfate Conjugation - Sulfation Oxcarbazepine [2]
MR001872 Oxcarbazepine R-licarbazepine Reduction - Reduction Oxcarbazepine [1]
MR000949 Oxcarbazepine 10-hydroxycarbazepine glucuronide metabolite Unclear Eslicarbazepine acetate [3]
MR000948 Oxcarbazepine Eslicarbazepine Reduction - Reduction Eslicarbazepine acetate [3]
MR000947 Oxcarbazepine Oxcarbazepine alcohol sulfate Unclear Eslicarbazepine acetate [3]
MR000950 Oxcarbazepine R-licarbazepine Reduction - Reduction Eslicarbazepine acetate [3]
References
1 The role of carbonyl reducing enzymes in oxcarbazepine in vitro metabolism in man. Chem Biol Interact. 2014 Sep 5;220:241-7.
2 The metabolism of 14C-oxcarbazepine in man Xenobiotica. 1986 Aug;16(8):769-78. doi: 10.3109/00498258609043567.
3 U. S. FDA Label -Eslicarbazepine acetate

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