Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001909)
Formula
SVG example
Hydroxylation
Reactant Paclitaxel Product 6alpha-hydroxypaclitaxel
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001908 Paclitaxel 3'-p-hydroxypaclitaxel Oxidation - Hydroxylation Paclitaxel [1]
MR001907 Paclitaxel 6alpha, 3'-p-dihydroxypaclitaxel Oxidation - Hydroxylation Paclitaxel [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011040 Taxol 6alpha-hydroxypaclitaxel Unclear - Unclear Taxol [3]
References
1 Update: influenza activity--United States MMWR Morb Mortal Wkly Rep. 1986 Mar 14;35(10):166-7.
2 [International council of nurses: the international voice of the nursing profession] Bol Oficina Sanit Panam. 1979 Aug;87(2):152-5.
3 The Quantification of Paclitaxel and Its Two Major Metabolites in Biological Samples by HPLC-MS/MS and Its Application in a Pharmacokinetic and Tumor Distribution Study in Xenograft Nude Mouse

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.