Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001925)
Formula	CYP3A4 ... Dehydrogenation
	Reactant	Paliperidone	Product	Risperidone
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
	Cytochrome P450 3A5 (CYP3A5)				DME Info
	Cytochrome P450 2D6 (CYP2D6)				DME Info
Metabolic Type	Oxidation - Dehydrogenation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001924	Paliperidone	9-hydroxyrisperidone	Unclear	Paliperidone	[1]

References
1	Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes. Drug Metab Dispos. 2001 Oct;29(10):1263-8.

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