Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001954)
Formula
rox
SVG example
Reactant PD-115934 Product PZA N-oxide
Reactant Info Product Info
Metabolic Enzyme Rifampicin monooxygenase (rox) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001952 PD-115934 9-desmethyl-PZA Unclear PD-115934 [1]
MR001953 PD-115934 N-demethyl-PZA Unclear PD-115934 [1]
References
1 The metabolism of pyrazoloacridine (NSC 366140) by cytochromes p450 and flavin monooxygenase in human liver microsomes. Clin Cancer Res. 2004 Feb 15;10(4):1471-80.

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