Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001953)
Formula	CYP3A4
	Reactant	PD-115934	Product	N-demethyl-PZA
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001952	PD-115934	9-desmethyl-PZA	Unclear	PD-115934	[1]
MR001954	PD-115934	PZA N-oxide	Unclear	PD-115934	[1]

References
1	The metabolism of pyrazoloacridine (NSC 366140) by cytochromes p450 and flavin monooxygenase in human liver microsomes. Clin Cancer Res. 2004 Feb 15;10(4):1471-80.

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