General Information of This Metabolic Reaction (MR) (ID: MR001952)
Formula
Reactant PD-115934 Product 9-desmethyl-PZA
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001953 PD-115934 N-demethyl-PZA Unclear PD-115934 [1]
MR001954 PD-115934 PZA N-oxide Unclear PD-115934 [1]
References
1 The metabolism of pyrazoloacridine (NSC 366140) by cytochromes p450 and flavin monooxygenase in human liver microsomes. Clin Cancer Res. 2004 Feb 15;10(4):1471-80.

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