Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001955)
Formula	NNMT
	Reactant	Peficitinib metabolite MH2	Product	Peficitinib metabolite MH1
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Nicotinamide N-methyltransferase (NNMT)				DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001958	Peficitinib	Peficitinib metabolite MH2	Unclear	Peficitinib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001956	Peficitinib metabolite MH4	Peficitinib metabolite MH1	Unclear	Peficitinib	[1]

References
1	Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function Clin Pharmacol Drug Dev. 2020 Aug;9(6):699-708. doi: 10.1002/cpdd.751.

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