Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001978)
Formula
SVG example
Demethylation
Reactant Lisofylline Product Pentoxifylline metabolite M7
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001981 Pentoxifylline Lisofylline Reduction - Reduction Pentoxifylline [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001980 Lisofylline Pentoxifylline metabolite M2 Oxidation - Hydroxylation Pentoxifylline [1]
MR001979 Lisofylline Pentoxifylline metabolite M3 Oxidation - Hydroxylation Pentoxifylline [1]
References
1 Metabolism of lisofylline and pentoxifylline in human liver microsomes and cytosol Drug Metab Dispos. 1996 Nov;24(11):1174-9.

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