Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002018)
Formula
CYP3A4 ...
SVG example
Hydrolysis
Reactant Phenelzine Product Phenethylamine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002020 Phenelzine 4- hydroxyphenelzine Oxidation - 4-Hydroxylation Phenelzine [1]
MR002019 Phenelzine Phenylacetic acid Hydrolysis - Hydrolysis Phenelzine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002015 Phenethylamine Phenylacetic acid Unclear Phenelzine [1]
References
1 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.

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