Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002019)
Formula
SVG example
Hydrolysis
Reactant Phenelzine Product Phenylacetic acid
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002020 Phenelzine 4- hydroxyphenelzine Oxidation - 4-Hydroxylation Phenelzine [1]
MR002018 Phenelzine Phenethylamine Hydrolysis - Hydrolysis Phenelzine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007824 Ipratropium Phenylacetic acid Hydrolysis - Hydrolysis Ipratropium [2]
MR008132 Penicillin Phenylacetic acid Unclear - Unclear Penicillin [3]
MR008108 Penicillin G Sodium Phenyl acetic acid Hydrolysis - Hydrolysis Penicillin G Sodium [4]
MR005608 Sodium phenylbutyrate Phenylacetic acid Oxidation - Oxidationn Sodium phenylbutyrate [5]
MR002015 Phenethylamine Phenylacetic acid Unclear Phenelzine [1]
MR009197 3-(phenyl)propanoic acid 3-(phenyl)acetic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [6]
MR004490 3'-Hydroxyphenylacetic acid Phenylacetic acid Unclear VS-12343 [7]
MR004498 3-(phenyl)propionic acid Phenylacetic acid Unclear VS-12343 [7]
⏷ Show the Full List of MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009198 3-(phenyl)acetic acid Benzoic acid Oxidation - Oxidation 3,4-Dihydroxycinnamic Acid [6]
References
1 Insights into the mechanisms of action of the MAO inhibitors phenelzine and tranylcypromine: a review J Psychiatry Neurosci. 1992 Nov;17(5):206-14.
2 Ipratropium bromide: drug metabolism and pharmacokinetics
3 Ligand-induced conformational change in penicillin acylase
4 A breakthrough in enzyme technology to fight penicillin resistance-industrial application of penicillin amidase
5 DrugBank(Pharmacology-Metabolism):Sodium phenylbutyrate
6 In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota
7 Biotransformation of two citrus flavanones by lactic acid bacteria in chemical defined medium

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