Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002071)
Formula
SVG example
Hydrolysis
Reactant Pitavastatin lactone Product Pitavastatin
Reactant Info Product Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008858 Pitavastatin-ester-Glu Pitavastatin lactone Unclear - Unclear Pitavastatin [1]
MR002070 Pitavastatin glucuronide Pitavastatin lactone Unclear Pitavastatin calcium [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008859 Pitavastatin lactone Pitavastatin lactone-ether-Glu Unclear - Unclear Pitavastatin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002072 Pitavastatin calcium Pitavastatin Unclear Pitavastatin calcium [2]
References
1 Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans
2 Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003 Jan;33(1):27-41.

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