Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008858)
Formula
SVG example
Unclear
Reactant Pitavastatin-ester-Glu Product Pitavastatin lactone
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008857 Pitavastatin Pitavastatin-ester-Glu Unclear - Unclear Pitavastatin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002070 Pitavastatin glucuronide Pitavastatin lactone Unclear Pitavastatin calcium [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008859 Pitavastatin lactone Pitavastatin lactone-ether-Glu Unclear - Unclear Pitavastatin [1]
MR002071 Pitavastatin lactone Pitavastatin Hydrolysis - Hydrolysis Pitavastatin calcium [2]
References
1 Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans
2 Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003 Jan;33(1):27-41.

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