Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008859)
Formula	Unclear
	Reactant	Pitavastatin lactone	Product	Pitavastatin lactone-ether-Glu
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008858	Pitavastatin-ester-Glu	Pitavastatin lactone	Unclear - Unclear	Pitavastatin	[1]
MR002070	Pitavastatin glucuronide	Pitavastatin lactone	Unclear	Pitavastatin calcium	[2]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002071	Pitavastatin lactone	Pitavastatin	Hydrolysis - Hydrolysis	Pitavastatin calcium	[2]

References
1	Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: similarities and difference in the metabolism of pitavastatin in monkeys and humans
2	Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization. Xenobiotica. 2003 Jan;33(1):27-41.

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