Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002165)
Formula
CYP1B1 ...
SVG example
Reactant Procarbazine Product Azoprocarbazine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1B1 (CYP1B1) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002164 Procarbazine Hydrazine Unclear Procarbazine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002160 Azoprocarbazine Azoxy-1-procarbazine Unclear Procarbazine [2], [3]
MR002159 Azoprocarbazine Methylazoxyprocarbazine Unclear Procarbazine [2], [3]
References
1 DrugBank(Pharmacology-Metabolism)Procarbazine
2 Plasma kinetics of procarbazine and azo-procarbazine in humans Anticancer Drugs. 2006 Jan;17(1):75-80. doi: 10.1097/01.cad.0000181591.85476.aa.
3 Quantitative analysis of procarbazine, procarbazine metabolites and chemical degradation products with application to pharmacokinetic studies J Chromatogr. 1982 May 14;229(2):397-407. doi: 10.1016/s0378-4347(00)84282-6.

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