Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002232)
Formula
SVG example
Degradation
Reactant Selenocystein Product Ammonia
Reactant Info Product Info
Metabolic Enzyme Selenocysteine lyase (SCLY) DME Info
Metabolic Type Oxidation - Degradation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002227 Selenide Selenocystein Reduction - Reduction Selenium [1], [2], [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002231 Selenocystein Methyl-selenol Oxidation - Degradation Selenium [1], [4], [5]
MR002229 Selenocystein Pyruvate Oxidation - Degradation Selenium [1], [6], [7]
MR002230 Selenocystein Selenocysteine selenoxidel Oxidation - Oxidation Selenium [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004250 Methylamine Ammonia Oxidation - Deamination Methylamine [8]
MR002235 Selenocysteine selenoxidel Ammonia Oxidation - Degradation Selenium [1]
MR004035 Urea NH3 Unclear Xanthine [9]
References
1 Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis. 1999 Sep;20(9):1657-66.
2 Biochemistry, Antioxidants. 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 JanC.
3 Enhanced selenocysteine biosynthesis for seleno-methylselenocysteine production in Bacillus subtilis. Appl Microbiol Biotechnol. 2023 May;107(9):2843-2854. doi: 10.1007/s00253-023-12482-8.
4 Antitumor Effects of Selenium. Int J Mol Sci. 2021 Oct 31;22(21):11844. doi: 10.3390/ijms222111844.
5 Exposure to the Methylselenol Precursor Dimethyldiselenide Induces a Reductive Endoplasmic Reticulum Stress in Saccharomyces cerevisiae. Int J Mol Sci. 2021 May 22;22(11):5467. doi: 10.3390/ijms22115467.
6 Effects of Selenium Enrichment on Dough Fermentation Characteristics of Baker's Yeast. Foods. 2023 Jun 11;12(12):2343. doi: 10.3390/foods12122343.
7 Multiomics understanding of improved quality in cherry radish (Raphanus sativus L. var. radculus pers) after foliar application of selenium nanomaterials. Sci Total Environ. 2022 Jun 10;824:153712. doi: 10.1016/j.scitotenv.2022.153712.
8 Deamination of methylamine and angiopathy; toxicity of formaldehyde, oxidative stress and relevance to protein glycoxidation in diabetes
9 Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism

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