Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002254)
Formula
SVG example
Oxidation
Reactant KMD-3241 Product KMD-3295
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002256 Silodosin KMD-3241 Oxidation - Dehydrogenation Silodosin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002255 KMD-3241 KMD-3241 glucuronide Conjugation - Glucuronidation Silodosin [1]
References
1 In vivo metabolic investigation of silodosin using UHPLC-QTOF-MS/MS and in silico toxicological screening of its metabolites J Mass Spectrom. 2016 Oct;51(10):867-882. doi: 10.1002/jms.3795.

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