Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002360)
Formula Reactant Tegaserod Product O-desmethyl tegaserod
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002361 Tegaserod . Hydrolysis - Hydrolysis Tegaserod [1]
MR002357 Tegaserod Tegaserod metabolite M43.2 Conjugation - N-Glucuronidation Tegaserod [1]
MR002358 Tegaserod Tegaserod metabolite M43.8 Conjugation - N-Glucuronidation Tegaserod [1]
MR002359 Tegaserod Tegaserod metabolite M45.3 Conjugation - N-Glucuronidation Tegaserod [1]
References
1 Clinical pharmacokinetics of tegaserod, a serotonin 5-HT(4) receptor partial agonist with promotile activity Clin Pharmacokinet. 2002;41(13):1021-42. doi: 10.2165/00003088-200241130-00002.

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