Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002474)
Formula
SVG example
Reactant UDP Product UTP
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002473 UMP UDP Unclear Uridine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002475 UDP DNA Unclear Uridine [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002476 UTP CTP Unclear Uridine [1], [4], [5]
MR002478 UTP RNA Unclear Uridine [1], [6], [3]
MR002477 UTP UDP-sugars Unclear Uridine [1]
References
1 Uridine and its nucleotides: biological actions, therapeutic potentials Trends Pharmacol Sci. 1999 May;20(5):218-25. doi: 10.1016/s0165-6147(99)01298-5.
2 Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation. Life Sci Alliance. 2023 Jun 22;6(9):e202302066. doi: 10.26508/lsa.202302066. Print 2023 Sep.
3 Uridine Inhibits Hepatocellular Carcinoma Cell Development by Inducing Ferroptosis. J Clin Med. 2023 May 18;12(10):3552. doi: 10.3390/jcm12103552.
4 Computational assessment of Withania somnifera phytomolecules as putative inhibitors of Mycobacterium tuberculosis CTP synthase PyrG. J Biomol Struct Dyn. 2023 Jul;41(11):4903-4916. doi: 10.1080/07391102.2022.2074142.
5 Structural basis for ligand binding modes of CTP synthase. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2026621118. doi: 10.1073/pnas.2026621118.
6 Decoding the 'Fifth' Nucleotide: Impact of RNA Pseudouridylation on Gene Expression and Human Disease. Mol Biotechnol. 2023 Jun 21. doi: 10.1007/s12033-023-00792-1.

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