Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002477)
Formula Reactant UTP Product UDP-sugars
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002474 UDP UTP Unclear Uridine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002476 UTP CTP Unclear Uridine [1], [2], [3]
MR002478 UTP RNA Unclear Uridine [1], [4], [5]
References
1 Uridine and its nucleotides: biological actions, therapeutic potentials Trends Pharmacol Sci. 1999 May;20(5):218-25. doi: 10.1016/s0165-6147(99)01298-5.
2 Computational assessment of Withania somnifera phytomolecules as putative inhibitors of Mycobacterium tuberculosis CTP synthase PyrG. J Biomol Struct Dyn. 2023 Jul;41(11):4903-4916. doi: 10.1080/07391102.2022.2074142.
3 Structural basis for ligand binding modes of CTP synthase. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2026621118. doi: 10.1073/pnas.2026621118.
4 Decoding the 'Fifth' Nucleotide: Impact of RNA Pseudouridylation on Gene Expression and Human Disease. Mol Biotechnol. 2023 Jun 21. doi: 10.1007/s12033-023-00792-1.
5 Uridine Inhibits Hepatocellular Carcinoma Cell Development by Inducing Ferroptosis. J Clin Med. 2023 May 18;12(10):3552. doi: 10.3390/jcm12103552.

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