Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002573)
Formula Reactant Cabazitaxel metabolite M1 Product Cabazitaxel metabolite M2
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002577 Cabazitaxel Cabazitaxel metabolite M1 Oxidation - Hydroxylation Cabazitaxel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002574 Cabazitaxel metabolite M2 Cabazitaxel metabolite M08b Oxidation - Cleavage Cabazitaxel [1]
References
1 A phase I open-label study investigating the disposition of [14C]-cabazitaxel in patients with advanced solid tumors Anticancer Drugs. 2015 Mar;26(3):350-8. doi: 10.1097/CAD.0000000000000185.

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