Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002584)
Formula
SVG example
Reactant 10,11-Epoxycarbamazepine Product 10,11-Dihydroxycarbamazepine
Reactant Info Product Info
Metabolic Enzyme EH domain-binding protein 1-like protein 1 (EHBP1L1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002588 Carbamazepine 10,11-Epoxycarbamazepine Oxidation - 10,11-Epoxidation Carbamazepine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002585 10,11-Epoxycarbamazepine 9-hydroxymethyl-10-carbamaoyl acridan Unclear Carbamazepine [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001867 R-licarbazepine Trans-10,11-dihydro-10,11-dihydroxycarbamazepine Oxidation - Oxidation Oxcarbazepine [3]
References
1 Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood Epilepsia. 1995 Mar;36(3):241-8. doi: 10.1111/j.1528-1157.1995.tb00991.x.
2 PharmGKB: A worldwide resource for pharmacogenomic information. Wiley Interdiscip Rev Syst Biol Med. 2018 Jul;10(4):e1417. (ID: PA165817070)
3 DrugBank(Pharmacology-Metabolism)Oxcarbazepine

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